Temperatures will be 10 to 15 degrees below average over much of the Midwest and East. Even Florida is shivering.

San Francisco 49ers star Christian McCaffrey could "potentially" be lost for the season with a knee injury, head coach Kyle Shanahan said Sunday night.

The Lake-effect snowstorm that severely affected parts of Buffalo, New York, Pennsylvania, and Michigan this Thanksgiving ...

The heavy lake effect snow prompted the Buffalo Bills to ask fans for help clearing snow out of Highmark Stadium ahead of the ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday Night Football, rumbling past them 35-10. Not only did this win ...

Russell Wilson and the Steelers are on the rise after another key win, as the 49ers continue to tumble. Who else won or lost in NFL Week 13?

Meteorological winter got underway on Sunday, but wintry weather arrived several days prior in the Great Lakes amid a holiday weekend filled with travel-snarling whiteouts and feet of snow. Bitterly ...

The snow has been falling heavy and fast across the Great Lakes region — but that did not stop the Buffalo Bills football game Sunday night. They dominated the visiting San Francisco 49ers in a ...

Bills quarterback Josh Allen and head coach Sean McDermott celebrated by making snow angels after Buffalo clinched its fifth ...

A Buffalo Bills fan was shirtless in below freezing temperatures and jumping in snow during the team's win over the 49ers.

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...