A novel program to bring liquid biopsies into clinical care for patients with advanced cancer has been launched in France. However, several barriers preventing a similar program in the United States ...

President-elect Donald Trump announced he will nominate Jay Bhattacharya, MD, PhD, of the Stanford University School of Medicine in California, to head the NIH. A professor of health policy, ...

Normal breast tissue harbors rare populations of aneuploid cells, displaying genetic changes often associated with invasive breast cancer—a finding that challenges the reliability of genomic profiling ...

For adults ages 27 to 45, vaccinating against human papillomavirus (HPV) is costlier and less effective than vaccinating younger people to prevent HPV-related cancers (Ann Intern Med 2024 Nov 26 [Epub ...

Major Finding: FastGlioma, an AI-based visual model, rapidly scores the degree of glioma infiltration in surgical samples. Concept: This approach represents a rapid, label-free surgical adjunct that ...

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International ...

Copyright held by the owner/author(s).

Major Finding: A dual function supracluster was engineered to increase radiosensitivity and antitumor immunity. Concept: Gold supraclusters carrying siRNA against LGALS1 (galectin-1) reshaped the ...

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.

Major Finding: An inhibitor of E17K-mutant AKT1 exhibits selective antitumor efficacy without inducing hyperglycemia. Concept: A salicylaldehyde-based compound binds the mutant lysine, as endogenous ...

Treatment with eflornithine led to clinically meaningful improvements in overall survival (OS) and progression-free survival (PFS) for patients with recurrent grade 3 IDH-mutant astrocytoma, an ...

The Reproducibility Project: Cancer Biology has clearly highlighted the need for published articles to contain more detail of exactly how each study was conducted. This page describes AACR journal ...