The NFC West is a bunched-up, crazy-tight race and it's probably going to stay that way during the final six weeks of the NFL regular season.

Dive into the San Francisco 49ers vs. Buffalo Bills showdown with a look at odds, predictions, and the best betting options.

With four games already in the books this week, fantasy managers will turn to the remainder of matchups, hoping to either ...

San Francisco 49ers vs Buffalo Bills showdown with essential stats, lineup predictions and injury updates you won’t want to ...

Green Bay's first of two 2022 first-round picks had arguably his two best games of the season the last two weeks.

John Lynch shared positives from San Francisco's supbar 2024 NFL season with NBC Sports Bay Area's Matt Maiocco on "49ers ...

San Francisco 49ers wide receiver Jauan Jennings faces the Bills in Orchard Park for Week 13's Sunday night matchup. Last ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

San Francisco 49ers quarterback Brock Purdy is expected to return to the field on Sunday against the Buffalo Bills after ...

With the Miami Dolphins taking a 30-17 loss to the Green Bay Packers on Thursday night, the Buffalo Bills can wrap up the AFC East for a fifth straight season o ...

The NFL is just about as unpredictable as the Buffalo weather at this time of the year, so the 49ers will take their ...

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...