Buffalo Bills running back James Cook looked phenomenal in his team's Week 13 win over the San Francisco 49ers, and his ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday Night Football, rumbling past them 35-10. Not only did this win ...

San Francisco coach Kyle Shanahan told reporters postgame that their star running back had injured the posterior cruciate ...

When the snow comes out in Buffalo, you know what comes next: snowballs are going to get thrown. (Related: hey, NFL fans, ...

The Buffalo Bills beat the San Francisco 49ers 35-10 in a game that was dominated by Josh Allen. Craig Carton, Danny Parkins, ...

Josh Allen expertly navigated snow-topped turf, finding the end zone in a multitude of fashions and even receiving credit for ...

Following a brutal 38-10 loss to the Green Bay Packers last week, things didn't get any easier for the San Francisco 49ers ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

Somehow Week 13 was worse than for the San Francisco 49ers than Week 12. The 49ers fell behind 21-3 at halftime and had a ...