The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

The San Francisco 49ers are up against the Buffalo Bills in Week 13. The 49ers have dealt with an array of injuries this ...

Buffalo Bills head coach Sean McDermott has ruled out tight end Dalton Kincaid for Sunday night's game against the San ...

The Bills’ defense has plenty of experience against 21 personnel because Miami runs it the second most of any team in the NFL ...

Providing the betting odds and our preview and prediction for the star-studded matchup between the San Francisco 49ers and ...

The San Francisco 49ers could have Brock Purdy back soon, as the quarterback was recently seen throwing passes in a video ...

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

Defeating the Bills on the road will be extremely difficult for the 49ers, but they do have a favorable matchup on defense.

The San Francisco 49ers announced the signing of offensive lineman Sebastian Gutierrez to the practice squad. To make room on ...

San Francisco 49ers quarterback Brock Purdy is expected to play in Sunday's game against the Buffalo Bills, head coach Kyle ...

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.