Legendary California pharmacy Central Drug Store will be closing its doors for the last time on Tuesday after 117 years.

Central Drug Store in the Excelsior District will be closing its doors on July 15 after over 100 years. Owner Jerry Tonelli announced he will be retiring.

Central Drug Store, a community staple in San Francisco's Excelsior District since 1908, will permanently shut down at the end of the day on July 15, 2025.

Family-owned Central Drug Store in San Francisco closes its doors after serving the community since the early 1900s, with owner Jerry Tonelli retiring after 50 years.

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