San Francisco 49ers star Christian McCaffrey left Sunday night’s 35-10 loss to the Buffalo Bills with a knee injury, but it ...

With Christian McCaffrey's health once again in question, Jordan Mason gets second chance to lead 49ers backfield.

The 49ers — who were already without Trent Williams, Nick Bosa and Deommodore Lenoir — saw Christian McCaffrey leave their ...

The San Francisco 49ers plan to place running backs Christian McCaffrey and Jordan Mason on injured reserve after suffering ...

As the San Francisco 49ers departed Buffalo in the wee hours Monday morning, they were bracing for the possibility that ...

As the San Francisco 49ers confirmed Christian McCaffrey suffered a likely season-ending injury, his backup, Jordan Mason, ...

The San Francisco 49ers entered this season with lofty aspirations. For the most part, their hopes have been dashed -- and ...

An extremely disappointing season for Christian McCaffrey, which encapsulates the distressing tone of the San Francisco 49ers ...

Per HC Kyle Shanahan, the 49ers are placing RB Christian McCaffrey on injured reserve due to a PCL injury in his right knee.

When will he be coming back? The post Christian McCaffrey Injury Update: What Is the Usual PCL Strain Recovery Time? appeared ...

Achilles tendinitis robbed San Francisco 49ers star Christian McCaffrey of the first eight games of the 2024 NFL season. A ...

The dark and gloomy 2024 season gets worse for the San Francisco 49ers. On Monday, Kyle Shanahan delivered the worst-case ...