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A Controversial Alzheimer’s Drug Has Gone Down in Flames
Cassava Sciences' simufilam failed a Phase III trial for Alzheimer's disease, likely marking the end of a drug surrounded by allegations of poorly done and fraudulent research.
Trial of Controversial Alzheimer’s Drug Halted After Disappointing Results
Cassava Sciences said that its drug did not significantly reduce cognitive decline in 1,900 people with mild to moderate Alzheimer’s disease.
Controversial Alzheimer's drug trial halted
The trial, which involved patients with mild-to-moderate Alzheimer's disease, failed to show significant improvement in cognition and daily functioning compared to a placebo after 52 weeks, according to a Nov.
6h
Alzheimer’s disease: toxic protein is turned bad by immune enzyme, mouse study shows
Tau behaves abnormally in the brain in people with Alzheimer’s disease. This latest study points to a reason why.
5h
on MSN
Sen. Kaine applauds unanimous passage of bill to help combat Alzheimer’s disease
PORTSMOUTH, Va. (WAVY) – U.S. Senator Tim Kaine applauded the unanimous Senate passage of a bill to help combat Alzheimer’s ...
MedPage Today
5h
Alzheimer's Trials Fail; Blood Test Predicts Tau; Neuroscience Moves to Bluesky
Investigational simufilam failed to reduce cognitive or functional decline in Alzheimer's disease patients in the ReThink-ALZ ...
ScienceAlert on MSN
22h
Nasal Spray May Slow Alzheimer's Disease, Study in Mice Suggests
The active agent in the nasal spray, 2-bromopalmitate, carries a high risk of interfering with a number of processes, making ...
6h
on MSN
Machine learning reveals behaviors linked with early Alzheimer's, points to new treatments
Subtle signs of Alzheimer's disease can emerge decades before a diagnosis—often in the form of irregular behaviors that ...
MedPage Today
5h
International Working Group Discusses Diagnosing Alzheimer's Disease
The International Working Group discussed diagnosing Alzheimer's disease among cognitively unimpaired individuals in a ...
1d
on MSN
‘We’re living in uncertainty’: My sister has Alzheimer’s disease. How do I know the right time to take control of her finances?
Dear Quentin, I have two sisters who have developed Alzheimer’s disease. My younger sister is actually more severely ...
pharmaphorum
15h
End looms for Cassava's simufilam in Alzheimer's disease
Cassava Sciences' troubled development of Alzheimer's disease candidate simufilam looks like it may have finally reached the ...
Psychology Today
10h
The Relationship Between Music and Alzheimer’s Disease
Alzheimer’s is the most common type of dementia. Music therapy can improve mood and cognitive performance in Alzheimer’s ...
53m
Men at risk for heart disease may develop dementia 10 years before women, study says
Being at higher risk of heart disease may cause dementia to appear in men a decade before it will occur in similarly at-risk ...
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Cassava Sciences
Dementia
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