San Francisco fumbled the ball three times and lost all three. Brock Purdy dropped back to pass 20 times for 86 net yards.

After sparking the 49ers with a handful of impressive runs, Christian McCaffrey looked like himself early in the game against ...

Josh Allen expertly navigated snow-topped turf, finding the end zone in a multitude of fashions and even receiving credit for ...

T he Buffalo Bills dominated the San Francisco 49ers on Sunday Night Football, rumbling past them 35-10. Not only did this ...

The Bills got the job done in their own snowy backyard against the 49ers in NFL Week 13 action. In a 35-10 final, the Bills ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

The Week 13 Sunday slate closes with the Buffalo Bills (9-2) hosting the San Francisco 49ers (5-6) on Sunday Night Football.

A Buffalo Bills fan seemingly tried to use the snowy weather to their advantage on Sunday night as they appeared to toss a ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

The swagger is officially gone from this season's 49ers after another miserable outing in a 35-10 loss in Buffalo.

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

A picturesque setting of snow was the perfect backdrop for a Buffalo Bills team that has now won its fifth straight AFC East ...