Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

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Using a zebrafish xenograft model, we visualized BC cells migrating along cerebral veins in real time, confirming an extravascular pathway to the brain. We identified LRP8, a receptor upregulated in ...

The DNA damage response (DDR) plays an important role in maintaining genome stability (Jeggo et al, 2016). This is particularly apparent in cancer, where cells hijack DDR by upregulation of the key ...

The accumulation of mitochondrial precursor proteins in the cytosol due to mitochondrial dysfunction compromises cellular proteostasis and is a hallmark of diseases. Why non-imported precursors are ...

To estimate the readthrough efficiency of the AGO1 stop codon, these authors used a dual-luciferase reporter system in which AGO1-F-luc and R-luc were translated from separate mRNAs. AGO1-F-luc ...

Copine-6 is a calcium-sensitive phospholipid-binding protein of the evolutionarily conserved Copine family. In the central nervous system, Copine-6 regulates function of some neurotransmitter ...

During seedling deetiolation, plants adjust their development to expose photosynthetic tissues to sunlight, enabling the transition from heterotrophic to autotrophic growth. While various plant ...