Meanwhile, the 5-6 49ers are dealing with massive injury struggles. All-Pro left tackle Trent Williams, Defensive Player of ...

San Francisco 49ers TE George Kittle, LB Fred Warner and QB Brock Purdy outlined the team's performance on "SNF" against the Buffalo Bills.

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

The San Francisco 49ers are on the verge of falling out of contention for a playoff spot in the NFC after consecutive losses ...

First comes Brock Purdy, the team's star quarterback, who missed Week 12 with a right shoulder. While Purdy is still ...

San Francisco 49ers star quarterback Brock Purdy has been given an injury update in time for their Week 13 match up against ...

San Francisco 49ers quarterback Brock Purdy appears to be making strides in his recovery from a shoulder injury. During the ...

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

This week, Nick Bosa was asked about the 49ers' upcoming opponent, Bills quarterback Josh Allen. Here's what Bosa said. Q: ...

Wide receiver Chris Conley, linebacker Curtis Robinson and more San Francisco 49ers players shared what they're most grateful ...

Matt Maiocco shares the latest practice report for the San Francisco 49ers and Buffalo Bills ahead of their Week 13 game on ...

Nick Bosa speaks with reporters ahead of the San Francisco 49ers' Week 13 matchup against the Buffalo Bills on Sunday at ...