Injuries continue to mount around the NFL, and with Thanksgiving in the rearview mirror — and playoff berths already clinched — the push is on to get healthy for the stretch run. But a couple of teams that were thought to be among the playoff contenders at the start of the year have had their seasons derailed by trips to the trainer's table.

San Francisco 49ers running back Christian McCaffrey left Sunday night's contest versus the Buffalo Bills with what the team officially dubbed a knee injury. The 28-year-old gave himself before being touched, and immediately ran to the sideline before being taken to the locker room.

The San Francisco 49ers clearly struggled to adapt to the weather in Buffalo on Sunday night, and it showed, as the Bills cruised to a 35-10 victory. However,