The San Francisco 49ers are reportedly expected to lean on rookie running back Isaac Guerendo for the remainder of the 2024 ...

The 49ers — who were already without Trent Williams, Nick Bosa and Deommodore Lenoir — saw Christian McCaffrey leave their ...

Fans were excited when the Washington Commanders selected Rice wide receiver Luke McCaffrey in the third round of the 2024 ...

McCaffrey's old backfield mate discussed the trials and tribulations of a season-ending injury on his podcast.

Trevor Lawrence, Christian McCaffrey and Taysom Hill were among key players injured in Week 13 of the NFL season.

San Francisco 49ers running back Christian McCaffrey left Sunday night's contest versus the Buffalo Bills with what the team ...

The 49ers star running back was ruled out of Sunday Night Football after suffering a knee injury in the first half against ...

Christian McCaffrey is dealing with an injury again. The 49ers running back went down with a knee injury in the second ...

Copyright 2024 The Associated Press. All Rights Reserved. San Francisco 49ers running back Christian McCaffrey (23) runs ...

The San Francisco 49ers running back injured the PCL in his knee, an MRI confirmed Monday. San Francisco plans to place McCaffrey on injured reserve. He is expected to miss six weeks. Head coach Kyle ...

The 49ers running back, the reigning NFL offensive player of the year, is facing a six-week recovery for a knee injury.

Despite precautions, the 49ers made a costly decision in Week 13. McCaffrey was forced to play in harsh snowy conditions ...