Buffalo Bills wide receiver Jalen Virgil pounces on San Francisco 49ers wide receiver Deebo Samuel's fumble as the Bills' ...

San Francisco 49ers wide receiver Deebo Samuel returns the half-opening kick 60 yards into Buffalo Bills territory.

Samuel pulled in four of his five targets for 20 yards with a lost fumble in Sunday's 35=10 loss to the Bills.

Brandon Allen is 2-8 in 10 career starts. One of them was against Josh Allen and the Bills but Brandon Allen wore No. 2 in ...

The tragedy of this 49ers’ season epitomized. For the first time since returning to the lineup in Week 10, McCaffrey looked ...

On a snowy night in Orchard Park, N.Y., the Buffalo Bills clinched the AFC East title with a dominant win over the San ...

The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFL West. Here are ...

Somehow Week 13 was worse than for the San Francisco 49ers than Week 12. The 49ers fell behind 21-3 at halftime and had a ...

ORCHARD PARK, NEW YORK – DECEMBER 01: Mack Hollins #13 of the Buffalo Bills celebrates after scoring a touchdown in the ...

McCaffrey slid down untouched in the backfield after taking a toss, then immediately went to the 49ers' medical tent and ...

One week after a 38-10 road loss to the Green Bay Packers that stood out as one of their ugliest defeats in years, the San ...