The NFL is just about as unpredictable as the Buffalo weather at this time of the year, so the 49ers will take their ...

Defensively, two of the 49ers’ best players this season are out and will not travel as defensive end Nick Bosa (obliques, ...

The San Francisco 49ers announced Friday that they have waived wide receiver Ronnie Bell ahead of their Sunday night game ...

Head coach Kyle Shanahan shared the final injury report on QB Brock Purdy, DL Nick Bosa and others and discussed the team's ...

The San Francisco 49ers have released their final injury report ahead of their Week 13 bout with the Buffalo Bills.

Purdy missed the 49ers' Week 12 contest versus the Green Bay Packers last Sunday with a right shoulder injury—a game San ...

San Francisco 49ers quarterback Brock Purdy is expected to play in Sunday’s game against the Buffalo Bills, head coach Kyle ...

San Francisco 49ers quarterback Brock Purdy is expected to return Sunday against the Buffalo Bills, head coach Kyle Shanahan ...

San Francisco 49ers quarterback Brock Purdy is expected to return to the field on Sunday against the Buffalo Bills after ...

San Francisco 49ers quarterback Brock Purdy appears to be making strides in his recovery from a shoulder injury. During the ...

Missed the last seven snaps of the loss to Packers and was placed on concussion protocol upon the 49ers’ return home, Banks ...

Left tackle Trent Williams (ankle) and rusher Nick Bosa (hip/oblique), who also did not play in Week 12, were also absent ...