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A Controversial Alzheimer’s Drug Has Gone Down in Flames
Cassava Sciences' simufilam failed a Phase III trial for Alzheimer's disease, likely marking the end of a drug surrounded by allegations of poorly done and fraudulent research.
Trial of controversial Alzheimer’s drug halted after disappointing results
Cassava Sciences announced Monday that the drug, simufilam, did not significantly reduce cognitive decline in people with mild to moderate Alzheimer’s disease in the trial.
Controversial Alzheimer's drug trial halted
The trial, which involved patients with mild-to-moderate Alzheimer's disease, failed to show significant improvement in cognition and daily functioning compared to a placebo after 52 weeks, according to a Nov.
51m
on MSN
Men at risk for heart disease may develop dementia 10 years before women, study says
Being at higher risk of heart disease may cause dementia to appear in men a decade before it will occur in similarly at-risk ...
6h
Alzheimer’s disease: toxic protein is turned bad by immune enzyme, mouse study shows
Tau behaves abnormally in the brain in people with Alzheimer’s disease. This latest study points to a reason why.
5h
on MSN
Sen. Kaine applauds unanimous passage of bill to help combat Alzheimer’s disease
PORTSMOUTH, Va. (WAVY) – U.S. Senator Tim Kaine applauded the unanimous Senate passage of a bill to help combat Alzheimer’s ...
MedPage Today
5h
Alzheimer's Trials Fail; Blood Test Predicts Tau; Neuroscience Moves to Bluesky
Investigational simufilam failed to reduce cognitive or functional decline in Alzheimer's disease patients in the ReThink-ALZ ...
ScienceAlert on MSN
22h
Nasal Spray May Slow Alzheimer's Disease, Study in Mice Suggests
The active agent in the nasal spray, 2-bromopalmitate, carries a high risk of interfering with a number of processes, making ...
1d
on MSN
‘We’re living in uncertainty’: My sister has Alzheimer’s disease. How do I know the right time to take control of her finances?
Dear Quentin, I have two sisters who have developed Alzheimer’s disease. My younger sister is actually more severely ...
MedPage Today
5h
International Working Group Discusses Diagnosing Alzheimer's Disease
The International Working Group discussed diagnosing Alzheimer's disease among cognitively unimpaired individuals in a ...
Psychology Today
10h
The Relationship Between Music and Alzheimer’s Disease
Alzheimer’s is the most common type of dementia. Music therapy can improve mood and cognitive performance in Alzheimer’s ...
1d
on MSN
Cassava Sciences’ stock craters after Alzheimer’s disease trial fails to meet its goals
Cassava Sciences Inc.’s stock tumbled 85% Monday to put it on track for its biggest-ever one-day decline, after the ...
8d
on MSN
Alzheimer's: Scientists Analyze Body Fluid to Find New Drugs for Disease
Alzheimer's disease—the most common form of dementia—is a progressive neurological disorder that causes brain cells to ...
GEN
7h
Alzheimer’s Disease Neurodegeneration Held Back in Mice Treated Using Enzyme Inhibiting Nasal Spray
In mice, inhibiting protein S-palmitoylation Counteracted accumulation of harmful proteins in neurons and delayed onset and progression of cognitive decline.
StudyFinds on MSN
7h
AI reveals Alzheimer’s subtle, invisible warning signs
Could a computer detect the first subtle signs of Alzheimer’s disease long before doctors diagnose the patient? Scientists ...
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