How major nuclear protein complexes control specialized gene regulation in cancer and beyond

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Scientists Flip an Alzheimer’s Risk Gene – and Reverse Key Hallmarks of the Disease

Summary: Researchers have created a new experimental model that reveals how changing a key Alzheimer’s risk gene can shift ...

Study overturns long-held model of how plants coordinate immune responses

Plants mobilize their immune defenses far earlier than scientists have believed for decades—and through a previously ...
Frontiers

Pharmacogenetics in Optimising Therapy of Infectious Diseases: Understanding Host Genetic Variants Influencing Drug Metabolism, Immune Response, and Adverse Drug Reactions

Pharmacogenetics and pharmacogenomics are increasingly recognised as playing a pivotal role in the advancement of personalised medicine, especially in the ...