Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of ...

Physiologic alterations in CHF, such as changes in absorption, distribution, metabolism, and elimination of drugs, can indeed alter loop diuretic pharmacokinetics; however, these effects do not fully ...

LOWER-NEPHRON nephrosis following exposure to carbon tetrachloride is a well established and fairly common entity. 1–6 Such a case was recently seen at the United States Public Health Service Hospital ...

Fluid accumulation producing edematous states is a common problem encountered in patients with CHF. Management of the edematous state usually includes diuresis in combination with fluid and sodium ...