The Bills return from their bye week with a tough test on Sunday Night Football. Here's a look ahead to the matchup.

The San Francisco 49ers and Buffalo Bills will clash on "Sunday Night Football." Here's how to watch the Week 13 NFL game live online or on TV.

The 49ers have been careful not to open practice windows for any of their players too early. With that in mind, if everything goes according to plan, Greenlaw could return to the field as early as Week 13 when San Francisco travels to the east coast for a primetime matchup against the Buffalo Bills at Highmark Stadium.

Here’s how you can watch, stream and listen to the game. Bills vs. 49ers will air on NBC. Mike Tirico will be on play-by-play with Cris Collinsworth doing color commentary and Melissa Stark serving as the sideline reporter. Buffalo Kickoff Live will air at 11 a.m. on WNLO and 11:30 a.m. on WIVB.

The Bills are back after a bye week and inching closer to clinching an AFC East title. The San Fransisco 49ers visit Orchard Park as the Bills are back in primetime. The game can be seen on NBC at 8:20 p.