Leprechaun 4: In Space is easily the best sequel in the franchise, and is arguably the only good movie of the entire bunch.
Alien, Event Horizon, and Pandorum are all among the absolute most terrifying sci-fi and horror movies set in space.
On Episode 184 of This Week In Space, Rod Pyle and Tariq Malik look at why space can be scary with a survey of some of the best (and some of the most laughable) movies about critters from outer space!