LNPs consist of ionizable lipids, which are critical for encapsulating RNA and enabling cellular uptake. Helper lipids contribute to the structural integrity and fusion with cell membranes.

Within tumors in the human body, there are immune cells (macrophages) capable of fighting cancer, but they have been unable ...

Explore how nanotechnology acts as the 'Convergence Engine' for AI materials discovery, CRISPR gene therapy delivery, and ...

Characterizing oligonucleotide aggregates is increasingly necessary as large nucleic acids and lipid nanoparticles (LNP) move beyond the lab and into production. Unfortunately, existing technologies ...

A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common chronic diseases like heart disease, diabetes, and cancer. A new process that ...

Interest in lipid nanoparticles (LNPs) as delivery vehicles for precision therapies in genetic diseases and cancers remains at an all-time high. Now, scientists from the University of Pennsylvania, ...

Researchers at Entos Pharmaceuticals report today in Cell that they have developed a particle that can deliver DNA and RNA to many tissues without triggering an immune response (2024, DOI: ...

Inspired by the design of space shuttles, researchers have invented a new way to synthesize a key component of lipid nanoparticles (LNPs), the revolutionary delivery vehicle for mRNA treatments ...

Cayman's LipidLaunch™ research-ready LNPs, reagent kits, and screening sets help researchers pursue lipid nanoparticles (LNPs) for the delivery of nucleic acid therapies. LipidLaunch™ Research Tools ...