Whenever there is a wound or infection, the body produces an inflammatory response. This is the body's first line of defense, and macrophages—cells of the innate immune system—play a key role: first, ...

The buzzy term gets blamed for many diseases. But it isn’t all bad. Credit...Pete Gamlen Supported by By Nina Agrawal Illustrations by Pete Gamlen Inflammation has become a bit of a dirty word. We ...

“If you cut yourself and the wound gets infected, it’ll become inflamed. There’s a reason for that: The inflammation brings in all the white blood cells that help you fight the infection,” says Eric ...

Chronic inflammation is both a driver and suppressor of cancer depending on context. Key players-NF-κB, IL-6, STAT3, TAMs, MDSCs, and Tregs-orchestrate a tumor-permissive microenvironment.

Long-term (chronic) inflammation in your body has been linked with several types of cancer, in addition to other serious conditions. One recent study found that 20% of cancer-related deaths were ...

Cortisol, the primary glucocorticoid hormone, plays a central role in the body's stress response and immune regulation. Released by the adrenal cortex via the hypothalamic-pituitary-adrenal (HPA) axis ...

Inflammation can feel like a localized fever, with redness, pain, heat and swelling. It’s how the body works to protect you after an injury, removing damaged tissue or invading bacteria and beginning ...