Overcoming acquired treatment resistance is one of the major challenges in the fight against cancer. While combination ...

In a world-first, scientists at Tel Aviv University have successfully 3D printed a tiny human heart using real human cells.

Engineers at the University of Pittsburgh are working to develop 3D-printed organic tissue models that mimic the behavior of living organs. Online cover of Science Advances, April issue. A ...

You may not be able to grow bigger muscles out of thin air, but you can 3D print them in microgravity, scientists at ETH Zurich have now established. "3D printing" refers to a type of manufacturing ...

Traditional animal models and simplified cell cultures often fail to capture human biology, limiting progress in biomedical research and drug development. Emerging microfluidic "Organ-on-Chip" ...

A new study provides a powerful way to study infections in environments that closely mimic human organs. The strategy, tested in a bone-marrow-on-chip model, was developed by researchers from the ...

Bioprinting holds the promise of engineering organs on demand. Now, researchers have solved one of the major bottlenecks—how to create the fine networks of blood vessels needed to keep organs alive.

Zachary Sexton and colleagues have developed a design platform that can rapidly generate vasculature trees that can then be bioprinted and used to successfully perfuse living tissue constructs. The ...

For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...