DNA sequences that regulate expression of the insulin gene are located within a region spanning ~400 bp that flank the transcription start site. This region, the insulin promoter, contains a number of ...

An international team, including researchers from HSE University, has created the first comprehensive map of ...

A recent study in genetic control elements revealed around 11,000 gene regulators active in every cell type, also known as housekeeping cis-regulatory elements (HK-CREs). These elements are vital in ...

DNA methylation is a key epigenome component that helps dictate how genes are expressed, contributing to normal cell and tissue differentiation during development, as well as the process of biological ...

Around 98.5% of human DNA is non-coding, meaning it doesn’t get copied to make proteins. A new study has connected many of these non-coding regions to the genes they affect and laid out guidelines for ...

Scientists have created the first comprehensive map of DNA quadruplexes, fleeting knot-like structures that play an outsized ...

A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in bacteria, archaea, and eukaryotes.

This study identifies around 11,000 housekeeping cis-regulatory elements (HK-CREs), revealing their important role in cellular stability and potential tumor suppression capability across diverse ...