CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.

'CpG islands' are often associated with promoter regions. A CpG island has traditionally been defined as a 200 bp region of DNA with a G+C content over 50% and an observed/expected CpG ratio of 0.6 or ...

This is a preview. Log in through your library . Abstract CpG islands (CGIs) are primarily promoter-associated genomic regions and are mostly unmethylated within highly methylated mammalian genomes.

In a first for the field of epigenomics, scientists at the Baylor College of Medicine (BCM) have demonstrated the feasibility of studying systemic differences in DNA methylation at the population ...