The mammalian immune system is an evolutionary wonder. It's capable of recognizing and destroying cancer cells, and it can deploy armies of antibodies against viruses, bacteria, parasites and fungi.

Effective immunity hinges on the ability to sense infection and cellular transformation. In humans, there is a specialized molecule on the surface of cells termed MR1. MR1 allows sensing of certain ...

WEST LAFAYETTE, Ind. — In the march of metastasis, a molecular trail of crumbs guides some cancer cells from the primary tumor to establish new colonies within the body. Blocking the cells’ ability to ...

The 2025 Nobel Prize in physiology or medicine has been awarded to a trio of scientists for unraveling how the immune system protects us from thousands of different microbes trying to invade our ...

TLS are clusters of lymphocytes that form in areas of chronic inflammation, including immune-hot tumors. These structures are critical in helping the immune system fight cancer, and their presence ...

A special group of immune cells known as regulatory T cells, or Tregs for short, became an overnight sensation when a trio of U.S. and Japanese scientists won the Nobel Prize in physiology or medicine ...

Findings from St. Jude Children's Research Hospital demonstrate that virtual memory T cells, a specialized group of immune cells, provide nonspecific immunity for infants early in life. The work stems ...

A small trial used designer CAR T cells to reboot the immune systems of patients with three autoimmune diseases, but it's still too early to say whether the treatment works in the long term. When you ...

Our study suggests that receptors on these myeloid cells get stimulated by this hormone and end up suppressing the immune system," said Cheng Cheng "Alec" Zhang, Ph.D., Professor of Physiology and a ...