FRANKFURT. The immune system of vertebrates is a powerful weapon against external pathogens and cancerous cells. T cells play a curcial role in this context. They carry a special receptor called the T ...
A cell's secrets can be divulged by its surface, decorated with tens to hundreds of thousands of molecules that help immune cells determine friend from foe. Some of those protruding molecules are ...
Harmonizing immunophenotyping assay designs facilitates integrating findings across trials, enabling biomarker identification and validation, revealing cohort-specific features and drug mechanisms as ...
It is well known that the biggest genetic risk factor for the autoimmune disease systemic lupus erythematosus (SLE) is major histocompatibility complex class II (MHC-II). What remains unclear is the ...
Why is plinabulin important for immuno-oncology? Plinabulin is a potent activator of GEF-H1, an immune defense protein that drives dendritic cell (DC) maturation, antigen cross-presentation and ...
In HepG2.117 cells, ALG-001075 achieved HBV DNA EC50 0.64 nM, outperforming canocapavir (5.8 nM) and neracorvir (24 nM) with ...
The seasonal influenza vaccine contains strains of viruses from distinct virus subtypes, but most people who are vaccinated will mount a strong immune response to one strain, leaving them vulnerable ...
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Survival and fracture risk with radium-223 therapy in metastatic castrate-resistant prostate cancer (mCRPC): A real-world analysis. Real-world treatment patterns in patients with BRCA 1/2-positive ...
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