Advances in organ and computer models are raising the prospect that some animal experiments could be eliminated. But there ...

LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Animal models have long shaped how biomedical research is conducted. They have influenced how diseases are studied, how ...

Every year, more than 100 million animals are used globally in biomedical research, yet over 90% of drugs that appear effective in animal trials fail during human clinical testing. 1 This staggering ...

Learn how animal-free 3D systems can reduce variability in drug discovery, leading to better human biology representation.

From studying disease mechanisms to testing new therapeutics, animal models have long served as essential tools in molecular biology research. However, animal models have limitations, including ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Researchers reveal that the guinea pig pre-implantation embryo is very similar to the human embryo, spurring a better understanding of infertility and early human development. CRCHUM researcher Sophie ...

A new computational model of the brain based closely on its biology and physiology has not only learned a simple visual category learning task exactly as well as lab animals, but even enabled the ...