There were also gaffes. After a Donavon Greene third-down drop on a deep ball, Louisville wideout Caullin Lacy fielded the ball on his own 32. He made his way down to the Hokies' five-yard line. Two plays later, tailback Keyjuan Brown punched it in a two-yard gain that gave Louisvill a lead it would never yield.

For about 30 minutes on Saturday afternoon, it looked like the Virginia Tech Hokies were about to win their second game in a row and move to 3-2 in ACC play. Unfortunately, a lopsided third quarter changed everything, and the No. 16 Louisville Cardinals (7-1, 4-1) came from behind to defeat the Hokies 28-16 (3-6, 2-3).

While the Hokies enter their second open date, their fans remain obsessed with the program’s coaching search and incessant chatter that recently deposed Penn State coach James Franklin could be

The No. 17 Louisville Cardinals (6-1) and the Virginia Tech Hokies (3-5) square off on Saturday, November 1, 2025 at Lane Stadium in a clash of ACC opponents. Read on to check out our prediction for this matchup.

This article was originally published on www.si.com/college/virginiatech as PFF Grades and Snap Counts from Virginia Tech's Week 10 Loss to No. 16 Louisville.