The loss was just the fifth in the past 21 games for the Astros, who had won the first two games of the series.

To put these two teams in perspective, the Astros still hold a comfortable lead in the American League West with a 52-35 record. On the opposite end of the spectrum, with the win, the Rockies improved to just 20-67 and are a staggering 35 games behind the first-place Dodgers in the National League West.

The Astros are heavily favored (-286 on the moneyline) when they square off against the Rockies (+230). The Houston Astros will give the start to Brandon Walter (1-1, 3.34 ERA), who is looking for win No.

Estrada, who boosted his average to .317, went 3 for 4. He tied the game, 2-2, with a two-run homer to left off Astros left-hander Brandon Walter in the first. Estrada’s infield grounder scored Kyle Farmer to put Colorado in front, 3-2, in the third.

Thairo Estrada hit a two-run homer in the first inning and drove in four runs to help the Colorado Rockies beat the Houston Astros 7-6 on Thursday

The Houston Astros placed infielder Luis Guillorme on the 10-day injured list with a strained right hamstring on Wednesday, the latest position player sidelined for the AL West leaders. The eight-year veteran Guillorme appeared in 12 games for the Astros,

D ENVER - The Houston Astros placed infielder Luis Guillorme on the 10-day injured list with a right hamstring strain before their game Wednesday against the Colorado Rockies, the team announced. Infielder Zack Short was called up from Triple-A Sugar Land to replace Guillorme on the active roster.