Fibroblastic reticular cells (FRCs) create T-cell-supportive niches within lung cancer tumors, facilitating T-cell migration, ...

Institute of Immunobiology-led research has made a significant breakthrough in understanding how the body combats lung cancer ...

Specialized cells help to create a nurturing environment in which tumour-fighting immune cells can thrive and work to ...

Their study reveals that specific cells, known as fibroblastic reticular cells (FRCs), create ...

and fibroblastic reticular cells (FRC). Conversely, stromal cell-derived chemokines such as CXCL13 govern the positioning of T and B cells, establishing SLO structures with segregated zones ...

Fibroblastic reticular cells (FRCs) create T-cell-supportive niches within lung cancer tumors, facilitating T-cell migration, clustering, and activation. This study highlights FRCs' potential as ...